Trappin ovine molecule (TOM), the ovine ortholog of elafin, is an acute phase reactant in the lung
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Trappin ovine molecule (TOM), the ovine ortholog of elafin, is an acute phase reactant in the lung.
As large animal models continue to play an important role in translating lung-directed therapeutic strategies from laboratory animals to humans, there is an increasing interest in the analysis of endogenous regulators of inflammation at both a genomic and a therapeutic level. To this end, we have sought to characterize the ovine ortholog of elafin, an important regulator of inflammation in huma...
متن کاملCALL FOR PAPERS Comparative Genomics Trappin ovine molecule (TOM), the ovine ortholog of elafin, is an acute phase reactant in the lung
Thomas I. Brown, Rohit Mistry, D. David Collie, Steven Tate, and Jean-Michel Sallenave Rayne Laboratory, Respiratory Medicine Unit, Medical Research Council Centre for Inflammation Research, University of Edinburgh, Edinburgh; Wellcome Trust Centre for Research in Comparative Respiratory Medicine, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian; and Molecular Genetics...
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ژورنال
عنوان ژورنال: Physiological Genomics
سال: 2004
ISSN: 1094-8341,1531-2267
DOI: 10.1152/physiolgenomics.00113.2004